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			function SM8_BannerWindowStatus(){SM8_MO=true;window.status=SM8_BannerItems[SM8_ThisBanner][1]; return true}
			function SM8_SwapBanner(){
				iNum=SM8_ThisBanner+1;if(iNum>=SM8_BannerItems.length)iNum=0;
				document.body_left_2.src=SM8_BannerItems[iNum][0].src; 
				SM8_ThisBanner=iNum;
				SM8_Timer=setTimeout('SM8_SwapBanner()',6000);
				if(SM8_MO){SM8_BannerWindowStatus();}else{window.status='';}
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			SM8_Timer=setTimeout('SM8_SwapBanner()',6000);
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function DHTMLNavBar_configureCookie(linkID) {
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	var cookie_name = '';
	var cookie_value = '';
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}
function DHTMLNavBar_setPLinkIDCookie(linkID){
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var DHTMLrunMouseOvers = false;
var aryDHTMLMoImages = new Array();
var DHTMLimageList = new Array();
var DHTMLTimerID=null;
var itmp=0;

function DHTMLMOImage() {
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	this.ptrImage = DHTMLNavBarMM_findObj(a[0]);
	this.imageMO = new Image();
	this.imageMO.src = a[1];
	this.HTMLname = a[0];
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// 0) html image name 1) mo image src 2)image Name for rollover key (rollover may have multiple mos for one html Image)
function DHTMLNavBarImagePreload() {
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function DHTMLNavBarMouseover() {
	var a = null;
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	var o = null;	
	if (DHTMLrunMouseOvers)
	{
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		a = DHTMLNavBarMouseover.arguments;
		imageKey = (a[2])?a[2]:a[0];
		if(!(aryDHTMLMoImages[imageKey].ptrImage))
			aryDHTMLMoImages[imageKey].ptrImage = DHTMLNavBarMM_findObj(a[0]);		
		if(aryDHTMLMoImages[imageKey] && (o = aryDHTMLMoImages[imageKey].ptrImage))
		{
			aryDHTMLMoImages[imageKey].OriginalSrc = a[1];
			aryDHTMLMoImages[imageKey].Moused = true;
			o.src = aryDHTMLMoImages[imageKey].imageMO.src;
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}

var DHTMLNavBarTemponload = null;
if (window.onload && window.onload != null)
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function DHTMLFullyLoaded() {
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		DHTMLNavBarTemponload();
	DHTMLrunMouseOvers = true;
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}	
function DHTMLNavBarMouseOutTimer() {
	if(DHTMLTimerID) 
		clearTimeout(DHTMLTimerID); 
	DHTMLTimerID = setTimeout("DHTMLNavBarLayerRestore()",5000);
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function DHTMLRestoreParent(layername) {
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}	
function DHTMLRestoreAll() {
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}	
function DHTMLNavBarMouseoverRestore() {
	var i = 0;
	var o = null;
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	{
		for (var i=0; i < DHTMLimageList.length; i++)
		{
			if (aryDHTMLMoImages[imageList[i]].Moused && (o = aryDHTMLMoImages[imageList[i]].ptrImage)) {
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				aryDHTMLMoImages[imageList[i]].Moused = false;
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	return true;
}	
function DHTMLNavBarLayerRestore() {
	for(var i=0;i < aryDHTMLLayerNames.length;i++)
	{
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			DHTMLNavBarRestoreLayers(aryDHTMLLayerNames[i]);		
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}	
function DHTMLNavBarArrayPushUnique(aryArray, varNewElement){
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	if(pushIt) 
		DHTMLNavBarArrayPush(aryArray, varNewElement);	
	
	return pushIt;
}
function DHTMLNavBarArrayPush(aryArray, varNewElement) {
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}	
function DHTMLNavBarArrayPop(aryArray) {
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	var varItemToPop = null;
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		aryArray[aryArray.length]=null;
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	return varItemToPop;
}
	
var registeredObjects = new Array();
//v3.0 name changed to avoid clash with possible other JS in content, this function complements of MM Dreamweaver
function DHTMLNavBarMM_findObj(n, d) {
	x = document.getElementById(n);
	return x;
}
	
var DHTMLNavBarTime         = 100;
var DHTMLNavBarTimes        = 2;
var DHTMLNavBarmoveDistance = 1;
var DHTMLNavBarThisLoc      = 325;
var aryDHTMLLayerNames      = new Array();
var aryDHTMLNavBarLayerInfo = new Array();
var aryDHTMLNavBarLayers    = new Array();
	
function DHTMLNavBarArrayContains()	{
	var a = DHTMLNavBarArrayContains.arguments;
	var foundit = false;
	for(var i=0; i < a[0].length && !foundit; i++) 
	{
		foundit = (a[1]==a[0][i]);
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	return foundit;
}
	
function DHTMLNavBarRegisterLayer()	{
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	var n = a[0];
	var d = a[1];
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		var mo = true;
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		var mo = false;	
	
	if(!(DHTMLNavBarArrayContains(aryDHTMLLayerNames,n)))
	{
		if(o = DHTMLNavBarMM_findObj(n))
		{
			aryDHTMLNavBarLayers[n] = o;
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			aryDHTMLNavBarLayerInfo[n] = new DHTMLNavBarLayer(n,d,mo);
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	}
}
	
// v3.0 name changed, this function complements of MM Dreamweaver with customizations
function DHTMLNavBarMM_showHideLayers()	{
	var i,p,v,x,obj,args = DHTMLNavBarMM_showHideLayers.arguments;
	if(args[args.length-1] != "menu") 
		DHTMLNavBarMouseOutTimer(); 
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	{
		if(!aryDHTMLNavBarLayers[args[i]]) {
			x = (args[i+2]=='show')?'hide':'show';
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		{
			v = args[i+2];
			aryDHTMLNavBarLayerInfo[args[i]].isDefault = false;
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			if (obj.style)
				obj.style.visibility = (v=='show')?'visible':(v='hide')?'hidden':v;
			else 
				obj.visibility = v;			
		}
	}
}
	
// v3.0 name changed, this function complements of MM Dreamweaver with customizations
function DHTMLNavBarMM_showHideGrandLayers() {
	var i,p,v,x,obj,args = DHTMLNavBarMM_showHideGrandLayers.arguments;
	if(args[args.length-1] != "menu") 
		DHTMLNavBarMouseOutTimer();
	for (var i=0; i < (args.length-2); i+=3)
	{
		if(!aryDHTMLNavBarLayers[args[i]]) {
			x = (args[i+2]=='show')?'hide':'show';
			DHTMLNavBarRegisterLayer(args[i],x);
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	 	if ((obj=aryDHTMLNavBarLayers[args[i]])!=null)
		{
			v = args[i+2];
			aryDHTMLNavBarLayerInfo[args[i]].isDefault = false;
	 			if(args[args.length-1] == "restore"){
				v = (v=='show')?'hide':'show';		
			}
			if (obj.style)
				obj.style.visibility = (v=='show')?'visible':(v='hide')?'hidden':v;
			else 
	 			obj.visibility = v;			
		}
	}
}
function DHTMLNavBarRestoreLayers()	{
	var i,p,v,obj,args = DHTMLNavBarRestoreLayers.arguments;
	for (var i=0; i < (args.length); i++)
	{		
	 	if (obj = aryDHTMLNavBarLayers[args[i]])
		{
			v = aryDHTMLNavBarLayerInfo[args[i]].defaultVisibility;
			var strobjid = obj.id;
			if (obj.style)
			{
				obj=obj.style;				
				v=(v=='show')?'visible':(v='hide')?'hidden':v;
			}
			obj.visibility = v;
			if (!aryDHTMLNavBarLayerInfo[args[i]].MOutLayer) 
				aryDHTMLNavBarLayerInfo[args[i]].isDefault=true;			
		}
	}
}
function DHTMLNavBarLayer()	{
	var a = DHTMLNavBarLayer.arguments;
	this.defaultVisibility = a[1];
	this.isDefault = true;
	this.MOutLayer = a[2];
}
	
var viz = "hide";
function DHTMLNavBarNavMove() {
	if(thisl==DHTMLNavBarMM_findObj("DHTMLNavBarScrollLayer"))	
	{
		if(thisl.style)
		{
			thisl=thisl.style;
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		{
			DHTMLNavBarThisLoc=325;
			DHTMLNavBarTimes--;
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	if (DHTMLNavBarTimes<=0)
	{
		otherl=DHTMLNavBarMM_findObj("DHTMLNavBarLayer");
		otherl.visibility=viz;
	}
	else setTimeout("DHTMLNavBarNavMove()",DHTMLNavBarTime);	
}
function DHTML_swapImgRestore()	{ 	
 	var i,x,a=document.Sliding_sr;
 	for(var i=0; a && i < a.length && (x=a[i]) && x.oSrc; i++) 
	{			
		x.src = x.oSrc;
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}
function DHTML_preloadImages() { 
 	var d=document;
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 	{
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			d.Sliding_p=new Array();	
		var i,j=d.Sliding_p.length,a=DHTML_preloadImages.arguments;
		for(var i=0; i < a.length; i++)
		{
	 		if (a[i].indexOf("#")!=0)
			{
				d.Sliding_p[j]=new Image;
				d.Sliding_p[j++].src=a[i];
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		}
	}
}
function DHTML_findObj(n, d) { 
	var p,i,x;
	if(!d) 
		d=document;	
	if((p=n.indexOf("?")) > 0 && parent.frames.length)
	{
	 	d=parent.frames[n.substring(p+1)].document;
		n=n.substring(0,p);
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	{
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	{
		x = DHTML_findObj(n,d.layers[i].document);
	}
	 if(!x && d.getElementById) 
		x=d.getElementById(n);	
		
	return x;
}
function DHTML_swapImage() { 
	var i,j=0,x,a=DHTML_swapImage.arguments;
	document.Sliding_sr=new Array;
	for(var i=0; i < (a.length-2); i+=3)
	{
		if ((x=DHTML_findObj(a[i]))!=null)
		{
			document.Sliding_sr[j++] = x;
			if(!x.oSrc)
				x.oSrc=x.src;			
			x.src = a[i+2];
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}
function DHTMLNavBarSwapRollover(swapimage,defaultimage,imageID) {
	if(imageID.length > 0 && document.getElementById(imageID))
	{
		if(swapimage.length > 0) 
			document.getElementById(imageID).src = "images/" + swapimage;
		else
			document.getElementById(imageID).src = "images/" + defaultimage;		
	}
}
window.onload = DHTMLFullyLoaded;
			

//-->
</script>
			
	
<table border="0" cellpadding="0" cellspacing="0">
	<tr>
		<td valign="top">
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				<tr id="pRow15" style="vertical-align: top; background-color: transparent;" >
					<td valign="top" style="" id="pLink15"><a href="body.cfm?id=15" target="" class="clMain1">Conditions Treated</a></td>
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			</table>
			<div id="lyr15" class="clLeft1" onMouseOut="DHTMLRestoreAll();">
				<table cellpadding="0" cellspacing="0" class="ChildNav1" border="0">
					<tr id="cRow15_1" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink15_1"><a href="body.cfm?id=21" target="" class="clSubb1">Alphabetical Conditions</a></td>
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					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
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					<tr id="cRow15_2" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink15_2"><a href="body.cfm?id=379" target="" class="clSubb1">Adult Conditions - Neurological</a></td>
					</tr>
					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
					</tr>
					<tr id="cRow15_3" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink15_3"><a href="body.cfm?id=23" target="" class="clSubb1">Pediatric Conditions</a></td>
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						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
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					<tr id="cRow15_4" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink15_4"><a href="body.cfm?id=24" target="" class="clSubb1">Brain Conditions [A—L]</a></td>
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					</tr>
					<tr id="cRow15_5" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink15_5"><a href="body.cfm?id=846" target="" class="clSubb1">Brain Conditions [M—Z]</a></td>
					</tr>
					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
					</tr>
					<tr id="cRow15_6" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink15_6"><a href="body.cfm?id=294" target="" class="clSubb1">Brain Tumor</a></td>
					</tr>
					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
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						<td valign="top" class="ChildNav1" style="" id="cLink15_7"><a href="body.cfm?id=25" target="" class="clSubb1">Spine Conditions</a></td>
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				<div id="endTablelyr15" style="height:1px;overflow:hidden;"></div><iframe id="Framelyr15" frameborder="0" style="background-color:transparent;left:0px;position:absolute;top:0px;width:100%;height:105;z-index:-1;filter:mask();"></iframe>
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		<div id="lryParentmain19" class="Parentmain1"  onmouseover="DHTMLRestoreAll();DHTMLNavBarMM_showHideLayers('lyr19','','show','menu');" onmouseout="DHTML_swapImgRestore();" onclick="DHTMLNavBar_configureCookie('19');">
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				<tr id="pRow19" style="vertical-align: top; background-color: transparent;" >
					<td valign="top" style="" id="pLink19"><a href="body.cfm?id=19" target="" class="clMain1">Find a Doctor</a></td>
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			</table>
			<div id="lyr19" class="clLeft1" onMouseOut="DHTMLRestoreAll();">
				<table cellpadding="0" cellspacing="0" class="ChildNav1" border="0">
					<tr id="cRow19_1" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink19_1"><a href="body.cfm?id=943" target="" class="clSubb1">Physicians</a></td>
					</tr>
					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
					</tr>
					<tr id="cRow19_2" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink19_2"><a href="body.cfm?id=840" target="" class="clSubb1">Research Scientists</a></td>
					</tr>
					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
					</tr>
					<tr id="cRow19_3" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink19_3"><a href="body.cfm?id=20" target="" class="clSubb1">Need Help?</a></td>
					</tr>
					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
					</tr>
				</table>
				<!--[if lte IE 6.5]>
				<div id="endTablelyr19" style="height:1px;overflow:hidden;"></div><iframe id="Framelyr19" frameborder="0" style="background-color:transparent;left:0px;position:absolute;top:0px;width:100%;height:45;z-index:-1;filter:mask();"></iframe>
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		</td>
		<td valign="top">
		<div id="lryParentmain16" class="Parentmain1"  onmouseover="DHTMLRestoreAll();DHTMLNavBarMM_showHideLayers('lyr16','','show','menu');" onmouseout="DHTML_swapImgRestore();" onclick="DHTMLNavBar_configureCookie('16');">
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				<tr id="pRow16" style="vertical-align: top; background-color: transparent;" >
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								  <h1 class="pagetitle" id="pagetitle"><strong>Faculty (BIRC)</strong> / Xiao Hu, PhD</h1>
                                
                                
		
		<h2 style="color: #000000"><strong>Xiao Hu, PhD</strong></h2>
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<td><img src="images/birc/hu2.jpg" border="0" alt="Dr. Hu" hspace="7" vspace="2" width="150" height="172" align="left" /> 
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<p align="left"><strong>Position</strong></p>
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<p>Assistant Professor in Residence</p>
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<p><strong>Gender </strong></p>
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<td width="10">&nbsp;</td>
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<p>Male</p>
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<p>&nbsp;</p>
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<p><strong>Hospital Affiliation </strong></p>
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<p>Ronald Reagan UCLA Medical Center<br />Department of Neurosurgery<br />David Geffen School of Medicine at UCLA<br />10833 Le Conte Avenue<br />Room 18-228 Semel Institute<br />Box 957039<br />Los Angeles , CA 90095 -7039</p>
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<p><strong>Contact </strong></p>
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<p>310-498-6136</p>
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<p style="color: #536895"><strong>EDUCATION </strong></p>
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<ul>
<li>B.S. Biomedical Engineering, University of Electronic Science and Technology of China, Chengdu, China (1992-1996)</li>
<li>M.S. Biomedical Engineering, University of Electronic Science and Technology of China, Chengdu, China (1996-1999)</li>
<li>Ph.D. Biomedical Engineering Interdepartmental Graduate Program, University of California, Los Angeles, California (1999-2004)</li>
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<p style="color: #536895"><strong>RESEARCH AREA </strong></p>
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<p>Dr Hu&rsquo;s research interests include clinical informatics and dynamics for improving diagnosis, treatment, monitoring and management of brain injury and stroke patients.He is Principal Investigator of two Ro1's for modeling dynamics of cerebral blood flow and intracranial pressure and the analysis of biomedical signals including intracranial pressure, cerebral blood flow velocity, arterial blood pressure, and heart rate variability. He is also active in research and development in medical informatics that involve large- scale clinical database, predictive data mining, and clinical decision support.</p>
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<p style="color: #536895"><strong>GRANTS </strong></p>
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<ul>
<li>&ldquo;Intracranial Pressure Latency as a Biomarker of Cerebral Vasculature Status&rdquo;, Exploratory Research Grant (R21), Role: Principal Investigator, 1/2008-1/2010. </li>
<li>&ldquo;Data Mining Based Noninvasive Intracranial Pressure Assessment&rdquo;, National Institute of Health, Exploratory Research Grant (R21), Role: Principal Investigator, 2/15/2007-2/14/2009. </li>
<li>"A Data Fusion Method for Bedside Monitoring of Lumped Cerebral Arterial Radii", National Institutes of Health, Exploratory Research Grant (R21), Role: Principal Investigator, 1/15/2007-1/14/2009.</li>
<li>"In Vivo CSF Shunt Hydrodynamics in Hydrocephalus", National Institutes of Health, Research Grant (R01), PI: Bergsneider, Marvin, Role: Key investigator, 2/4/2007-2/3/2011.</li>
<li>"Discover Association between Intracranial Pressure Pulse Morphology and Abnormalities in CT Brain Images of Head Injury Patients", UCLA Core Faculty Research Grant Role: Principal Investigator, 7/1/2008-7/1/2009.</li>
</ul>
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<p style="color: #536895"><strong>LINKS </strong></p>
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<ul>
<li><a href="body.cfm?id=871">Neural Systems and Dynamics Laboratory (NSDL)</a></li>
<li><a href="http://neurosurgery.ucla.edu">http://neurosurgery.ucla.edu</a></li>
</ul>
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<p style="color: #536895"><strong>AWARDS/INVENTIONS </strong></p>
</td>
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<td style="border: #d7e1e3 1px solid">
<ul>
<li>2008-2009 UCLA Clinical and Translational Science Institute Scholar.</li>
<li>Honorary thesis, University of Electronic Science and Technology of China/ Chengdu, China, 06/1999</li>
<li>Graduation with Honor Granted from the Ministry of Electronics Industry of China, University of Electronic Science and Technology of China, Chengdu, China, 06/1996</li>
</ul>
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<p style="color: #536895"><strong>PUBLICATIONS (recent articles)</strong></p>
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<td style="border: #d7e1e3 1px solid"><ol>
<li>Hu X, Nenov V, Glenn TC, Steiner LA, Czosnyka M, Bergsneider M, and Martin N. Nonlinear analysis of cerebral hemodynamic and intracranial pressure signals for characterization of autoregulation. IEEE Transactions on Biomedical Engineering 2006; 53: 195-209. </li>
<li>Hu X, Alwan AA, Rubinstein EH, and Bergsneider M. Reduction of compartment compliance increases venous flow pulsatility and lowers apparent vascular compliance: Implications for cerebral blood flow hemodynamics. Medical Engineering &amp; Physics 2006; 28: 304-314.</li>
<li>Hu X, Nenov V, Bergsneider M, Glenn TC, Paul V, and Martin N Estimation of Hidden State Variables of the Intracranial System Using Constrained Nonlinear Kalman Filters. IEEE Transactions on Biomedical Engineering 2007; 54(4): 597-610.</li>
<li>Hu X, Nenov V, Paul V, and Bergsneider M. Characterization of Interdependency between Intracranial Pressure and Heart Variability Signals: a Causal Spectral Measure and a Generalized Synchronization Measure. IEEE Transactions on Biomedical Engineering 2007; 54(8):1407-17.</li>
<li>Vespa PM, Miller C, Hu X, Nenov V, Buxey F, Martin NA. Intensive care unit robotic telepresence facilitates rapid physician response to unstable patients and decreased cost in neurointensive care. Surg Neurol. 2007 Apr;67(4):331-7. </li>
<li>Hu X, Miller C, Vespa P and Bergsneider M Adaptive computation of approximate entropy and its application in integrative analysis of irregularity of heart rate variability and intracranial pressure signals. Medical engineering &amp; physics(2008) 30 631-9.</li>
<li>Hu X, Xu P, Lee D J, Vespa P, Baldwin K and Bergsneider M. An algorithm for extracting intracranial pressure latency relative to electrocardiogram R wave. Physiological measurement (2008) 29 459-71.</li>
<li>Xu P, Bergsneider M, Hu X Pulse Onset Detection using Neighbor Pulse-Based Signal Enhancement. Medical engineering &amp; physics (2008) in Press.</li>
<li>Bergsneider M, Miller C, Vespa P M and Hu X 2008 Surgical management of adult hydrocephalus Neurosurgery 62 Suppl 2 SHC643-SHC59; discussion SHC59-SHC60</li>
<li>Hu X, Subudhi AW, Xu P, Asgari S, Roach RC, Bergsneider M. Inferring cerebrovascular changes from latencies of systemic and intracranial pulses: a model-based latency subtraction algorithm. J Cereb Blood Flow Metab 29:688-697</li>
<li>Hu X, Xu P, Scalzo F, Vespa P, Bergsneider M. Morphological clustering and analysis of continuous intracranial pressure. IEEE Trans Biomed Eng 56:696-705</li>
<li><font size="3"><span style="FONT-FAMILY: 'Arial','sans-serif'">Scalzo F, Xu P, Asgari S, Bergsneider M, Hu X. Regression Analysis for Peak&nbsp; Designation in&nbsp; Intracranial Pressure Signals. Medical &amp; Biological Engineering Computing (Accepted)</span><span style="COLOR: #1f497d"></span></font></li>
</ol>
<p><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;cmd=Search&amp;itool=pubmed_AbstractPlus&amp;term=Xiao%20Hu%5BAuthor%5D" target="_blank">Read my PubMed publications</a></p>
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