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	<title>Projects (BIRC) - UCLA</title>
	
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	<meta name="description" content="Projects (BIRC) Research - Brain Injury Research Center (BIRC) at UCLA - The purpose of the UCLA Brain Injury Research Center (BIRC) is to maintain a comprehensive basic and clinical scientific program in the field of TBI emphasizing translational research to develop effective therapies for head injured patients.">
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			function SM8_BannerWindowStatus(){SM8_MO=true;window.status=SM8_BannerItems[SM8_ThisBanner][1]; return true}
			function SM8_SwapBanner(){
				iNum=SM8_ThisBanner+1;if(iNum>=SM8_BannerItems.length)iNum=0;
				document.body_left_2.src=SM8_BannerItems[iNum][0].src; 
				SM8_ThisBanner=iNum;
				SM8_Timer=setTimeout('SM8_SwapBanner()',6000);
				if(SM8_MO){SM8_BannerWindowStatus();}else{window.status='';}
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			SM8_Timer=setTimeout('SM8_SwapBanner()',6000);
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function DHTMLNavBar_configureCookie(linkID) {
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	var cookie_name = '';
	var cookie_value = '';
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}
function DHTMLNavBar_setPLinkIDCookie(linkID){
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var DHTMLrunMouseOvers = false;
var aryDHTMLMoImages = new Array();
var DHTMLimageList = new Array();
var DHTMLTimerID=null;
var itmp=0;

function DHTMLMOImage() {
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	this.ptrImage = DHTMLNavBarMM_findObj(a[0]);
	this.imageMO = new Image();
	this.imageMO.src = a[1];
	this.HTMLname = a[0];
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// 0) html image name 1) mo image src 2)image Name for rollover key (rollover may have multiple mos for one html Image)
function DHTMLNavBarImagePreload() {
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function DHTMLNavBarMouseover() {
	var a = null;
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	var o = null;	
	if (DHTMLrunMouseOvers)
	{
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		a = DHTMLNavBarMouseover.arguments;
		imageKey = (a[2])?a[2]:a[0];
		if(!(aryDHTMLMoImages[imageKey].ptrImage))
			aryDHTMLMoImages[imageKey].ptrImage = DHTMLNavBarMM_findObj(a[0]);		
		if(aryDHTMLMoImages[imageKey] && (o = aryDHTMLMoImages[imageKey].ptrImage))
		{
			aryDHTMLMoImages[imageKey].OriginalSrc = a[1];
			aryDHTMLMoImages[imageKey].Moused = true;
			o.src = aryDHTMLMoImages[imageKey].imageMO.src;
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}

var DHTMLNavBarTemponload = null;
if (window.onload && window.onload != null)
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function DHTMLFullyLoaded() {
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		DHTMLNavBarTemponload();
	DHTMLrunMouseOvers = true;
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}	
function DHTMLNavBarMouseOutTimer() {
	if(DHTMLTimerID) 
		clearTimeout(DHTMLTimerID); 
	DHTMLTimerID = setTimeout("DHTMLNavBarLayerRestore()",5000);
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function DHTMLRestoreParent(layername) {
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}	
function DHTMLRestoreAll() {
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}	
function DHTMLNavBarMouseoverRestore() {
	var i = 0;
	var o = null;
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	{
		for (var i=0; i < DHTMLimageList.length; i++)
		{
			if (aryDHTMLMoImages[imageList[i]].Moused && (o = aryDHTMLMoImages[imageList[i]].ptrImage)) {
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				aryDHTMLMoImages[imageList[i]].Moused = false;
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	return true;
}	
function DHTMLNavBarLayerRestore() {
	for(var i=0;i < aryDHTMLLayerNames.length;i++)
	{
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			DHTMLNavBarRestoreLayers(aryDHTMLLayerNames[i]);		
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}	
function DHTMLNavBarArrayPushUnique(aryArray, varNewElement){
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	if(pushIt) 
		DHTMLNavBarArrayPush(aryArray, varNewElement);	
	
	return pushIt;
}
function DHTMLNavBarArrayPush(aryArray, varNewElement) {
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}	
function DHTMLNavBarArrayPop(aryArray) {
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	var varItemToPop = null;
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		aryArray[aryArray.length]=null;
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	return varItemToPop;
}
	
var registeredObjects = new Array();
//v3.0 name changed to avoid clash with possible other JS in content, this function complements of MM Dreamweaver
function DHTMLNavBarMM_findObj(n, d) {
	x = document.getElementById(n);
	return x;
}
	
var DHTMLNavBarTime         = 100;
var DHTMLNavBarTimes        = 2;
var DHTMLNavBarmoveDistance = 1;
var DHTMLNavBarThisLoc      = 325;
var aryDHTMLLayerNames      = new Array();
var aryDHTMLNavBarLayerInfo = new Array();
var aryDHTMLNavBarLayers    = new Array();
	
function DHTMLNavBarArrayContains()	{
	var a = DHTMLNavBarArrayContains.arguments;
	var foundit = false;
	for(var i=0; i < a[0].length && !foundit; i++) 
	{
		foundit = (a[1]==a[0][i]);
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	return foundit;
}
	
function DHTMLNavBarRegisterLayer()	{
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	var n = a[0];
	var d = a[1];
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		var mo = true;
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		var mo = false;	
	
	if(!(DHTMLNavBarArrayContains(aryDHTMLLayerNames,n)))
	{
		if(o = DHTMLNavBarMM_findObj(n))
		{
			aryDHTMLNavBarLayers[n] = o;
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			aryDHTMLNavBarLayerInfo[n] = new DHTMLNavBarLayer(n,d,mo);
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	}
}
	
// v3.0 name changed, this function complements of MM Dreamweaver with customizations
function DHTMLNavBarMM_showHideLayers()	{
	var i,p,v,x,obj,args = DHTMLNavBarMM_showHideLayers.arguments;
	if(args[args.length-1] != "menu") 
		DHTMLNavBarMouseOutTimer(); 
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	{
		if(!aryDHTMLNavBarLayers[args[i]]) {
			x = (args[i+2]=='show')?'hide':'show';
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		{
			v = args[i+2];
			aryDHTMLNavBarLayerInfo[args[i]].isDefault = false;
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			if (obj.style)
				obj.style.visibility = (v=='show')?'visible':(v='hide')?'hidden':v;
			else 
				obj.visibility = v;			
		}
	}
}
	
// v3.0 name changed, this function complements of MM Dreamweaver with customizations
function DHTMLNavBarMM_showHideGrandLayers() {
	var i,p,v,x,obj,args = DHTMLNavBarMM_showHideGrandLayers.arguments;
	if(args[args.length-1] != "menu") 
		DHTMLNavBarMouseOutTimer();
	for (var i=0; i < (args.length-2); i+=3)
	{
		if(!aryDHTMLNavBarLayers[args[i]]) {
			x = (args[i+2]=='show')?'hide':'show';
			DHTMLNavBarRegisterLayer(args[i],x);
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	 	if ((obj=aryDHTMLNavBarLayers[args[i]])!=null)
		{
			v = args[i+2];
			aryDHTMLNavBarLayerInfo[args[i]].isDefault = false;
	 			if(args[args.length-1] == "restore"){
				v = (v=='show')?'hide':'show';		
			}
			if (obj.style)
				obj.style.visibility = (v=='show')?'visible':(v='hide')?'hidden':v;
			else 
	 			obj.visibility = v;			
		}
	}
}
function DHTMLNavBarRestoreLayers()	{
	var i,p,v,obj,args = DHTMLNavBarRestoreLayers.arguments;
	for (var i=0; i < (args.length); i++)
	{		
	 	if (obj = aryDHTMLNavBarLayers[args[i]])
		{
			v = aryDHTMLNavBarLayerInfo[args[i]].defaultVisibility;
			var strobjid = obj.id;
			if (obj.style)
			{
				obj=obj.style;				
				v=(v=='show')?'visible':(v='hide')?'hidden':v;
			}
			obj.visibility = v;
			if (!aryDHTMLNavBarLayerInfo[args[i]].MOutLayer) 
				aryDHTMLNavBarLayerInfo[args[i]].isDefault=true;			
		}
	}
}
function DHTMLNavBarLayer()	{
	var a = DHTMLNavBarLayer.arguments;
	this.defaultVisibility = a[1];
	this.isDefault = true;
	this.MOutLayer = a[2];
}
	
var viz = "hide";
function DHTMLNavBarNavMove() {
	if(thisl==DHTMLNavBarMM_findObj("DHTMLNavBarScrollLayer"))	
	{
		if(thisl.style)
		{
			thisl=thisl.style;
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		{
			DHTMLNavBarThisLoc=325;
			DHTMLNavBarTimes--;
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	if (DHTMLNavBarTimes<=0)
	{
		otherl=DHTMLNavBarMM_findObj("DHTMLNavBarLayer");
		otherl.visibility=viz;
	}
	else setTimeout("DHTMLNavBarNavMove()",DHTMLNavBarTime);	
}
function DHTML_swapImgRestore()	{ 	
 	var i,x,a=document.Sliding_sr;
 	for(var i=0; a && i < a.length && (x=a[i]) && x.oSrc; i++) 
	{			
		x.src = x.oSrc;
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}
function DHTML_preloadImages() { 
 	var d=document;
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 	{
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			d.Sliding_p=new Array();	
		var i,j=d.Sliding_p.length,a=DHTML_preloadImages.arguments;
		for(var i=0; i < a.length; i++)
		{
	 		if (a[i].indexOf("#")!=0)
			{
				d.Sliding_p[j]=new Image;
				d.Sliding_p[j++].src=a[i];
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		}
	}
}
function DHTML_findObj(n, d) { 
	var p,i,x;
	if(!d) 
		d=document;	
	if((p=n.indexOf("?")) > 0 && parent.frames.length)
	{
	 	d=parent.frames[n.substring(p+1)].document;
		n=n.substring(0,p);
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	{
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	{
		x = DHTML_findObj(n,d.layers[i].document);
	}
	 if(!x && d.getElementById) 
		x=d.getElementById(n);	
		
	return x;
}
function DHTML_swapImage() { 
	var i,j=0,x,a=DHTML_swapImage.arguments;
	document.Sliding_sr=new Array;
	for(var i=0; i < (a.length-2); i+=3)
	{
		if ((x=DHTML_findObj(a[i]))!=null)
		{
			document.Sliding_sr[j++] = x;
			if(!x.oSrc)
				x.oSrc=x.src;			
			x.src = a[i+2];
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}
function DHTMLNavBarSwapRollover(swapimage,defaultimage,imageID) {
	if(imageID.length > 0 && document.getElementById(imageID))
	{
		if(swapimage.length > 0) 
			document.getElementById(imageID).src = "images/" + swapimage;
		else
			document.getElementById(imageID).src = "images/" + defaultimage;		
	}
}
window.onload = DHTMLFullyLoaded;
			

//-->
</script>
			
	
<table border="0" cellpadding="0" cellspacing="0">
	<tr>
		<td valign="top">
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				<tr id="pRow15" style="vertical-align: top; background-color: transparent;" >
					<td valign="top" style="" id="pLink15"><a href="body.cfm?id=15" target="" class="clMain1">Conditions Treated</a></td>
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			</table>
			<div id="lyr15" class="clLeft1" onMouseOut="DHTMLRestoreAll();">
				<table cellpadding="0" cellspacing="0" class="ChildNav1" border="0">
					<tr id="cRow15_1" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink15_1"><a href="body.cfm?id=21" target="" class="clSubb1">Alphabetical Conditions</a></td>
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					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
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					<tr id="cRow15_2" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink15_2"><a href="body.cfm?id=379" target="" class="clSubb1">Adult Conditions - Neurological</a></td>
					</tr>
					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
					</tr>
					<tr id="cRow15_3" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink15_3"><a href="body.cfm?id=23" target="" class="clSubb1">Pediatric Conditions</a></td>
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						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
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					<tr id="cRow15_4" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink15_4"><a href="body.cfm?id=24" target="" class="clSubb1">Brain Conditions [A—L]</a></td>
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					</tr>
					<tr id="cRow15_5" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink15_5"><a href="body.cfm?id=846" target="" class="clSubb1">Brain Conditions [M—Z]</a></td>
					</tr>
					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
					</tr>
					<tr id="cRow15_6" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink15_6"><a href="body.cfm?id=294" target="" class="clSubb1">Brain Tumor</a></td>
					</tr>
					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
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						<td valign="top" class="ChildNav1" style="" id="cLink15_7"><a href="body.cfm?id=25" target="" class="clSubb1">Spine Conditions</a></td>
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				<div id="endTablelyr15" style="height:1px;overflow:hidden;"></div><iframe id="Framelyr15" frameborder="0" style="background-color:transparent;left:0px;position:absolute;top:0px;width:100%;height:105;z-index:-1;filter:mask();"></iframe>
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		<div id="lryParentmain19" class="Parentmain1"  onmouseover="DHTMLRestoreAll();DHTMLNavBarMM_showHideLayers('lyr19','','show','menu');" onmouseout="DHTML_swapImgRestore();" onclick="DHTMLNavBar_configureCookie('19');">
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				<tr id="pRow19" style="vertical-align: top; background-color: transparent;" >
					<td valign="top" style="" id="pLink19"><a href="body.cfm?id=19" target="" class="clMain1">Find a Doctor</a></td>
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			</table>
			<div id="lyr19" class="clLeft1" onMouseOut="DHTMLRestoreAll();">
				<table cellpadding="0" cellspacing="0" class="ChildNav1" border="0">
					<tr id="cRow19_1" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink19_1"><a href="body.cfm?id=943" target="" class="clSubb1">Physicians</a></td>
					</tr>
					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
					</tr>
					<tr id="cRow19_2" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink19_2"><a href="body.cfm?id=840" target="" class="clSubb1">Research Scientists</a></td>
					</tr>
					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
					</tr>
					<tr id="cRow19_3" style="vertical-align: top; background-color: transparent;"  onmouseover="">
						<td valign="top" class="ChildNav1" style="" id="cLink19_3"><a href="body.cfm?id=20" target="" class="clSubb1">Need Help?</a></td>
					</tr>
					<tr>
						<td valign="top"><img alt="" src='images/c_btwn.gif'></td>
					</tr>
				</table>
				<!--[if lte IE 6.5]>
				<div id="endTablelyr19" style="height:1px;overflow:hidden;"></div><iframe id="Framelyr19" frameborder="0" style="background-color:transparent;left:0px;position:absolute;top:0px;width:100%;height:45;z-index:-1;filter:mask();"></iframe>
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		</td>
		<td valign="top">
		<div id="lryParentmain16" class="Parentmain1"  onmouseover="DHTMLRestoreAll();DHTMLNavBarMM_showHideLayers('lyr16','','show','menu');" onmouseout="DHTML_swapImgRestore();" onclick="DHTMLNavBar_configureCookie('16');">
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				<tr id="pRow16" style="vertical-align: top; background-color: transparent;" >
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								  <h1 class="pagetitle" id="pagetitle"><strong>Brain Injury Research Center (BIRC)</strong> / Projects (BIRC)</h1>
                                
                                
		
		<h2>Projects <br />
</h2>
<h3>&nbsp;&nbsp;</h3>
<h3>We have spent several years describing the acute state of cerebral hyperglycolisis following traumatic brain injury. </h3>
<p>
<strong>The most impressive finding is that after this acute period the brain enters a state of metabolic depression. </strong>Of the many mechanisms behind this metabolic depression (disconnection, cell death, reduction in energy need, etc) for tissue which is intact and appearing to be responding (behavioral recovery) this may simply be due to a lack of fuel. 
</p>
<p>
We now seek to identify the metabolic destination of cerebral glucose taken up after traumatic brain injury, thereby discovering alternative metabolic pathways receptive to interventions (metabolic therapy) to enhance cellular and functional recovery, which in turn may lead to fundamental changes in the future of TBI patient management. 
</p>
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			<td align="center" bgcolor="#eeeeee"><a href="workfiles/birc_documents/Birc_Projects.pdf" target="_blank"><span style="font-weight: 100; font-size: 9px; color: #000000">Download and Print (PDF) </span></a></td>
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<p>
One of the unique strengths of the UCLA BIRC program is the translational nature of the research. The BIRC has been able to take our new findings from our basic science research and confirm the observations clinically and then take new clinical problems and test solutions in the basic science laboratories. BIRC consists of both a clinical and basic science efforts which are shown in the figure. 
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<a href="workfiles/birc_documents/Birc_Projects.pdf" target="_blank">Download and print BIRC Programs (PDF)</a> 
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<p>
An important Brain Injury Research Center initiative is to educate children, teenagers, and adults about basic neuroscience, share facts about traumatic brain injury and instill habits to protect the brain from injury. 
</p>
<p>
<a href="body.cfm?id=628">Education Program &gt;&gt;</a> 
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