Neurosurgical Diseases and Disorders (M-Z) / Thyrotroph (TSH) Secreting Adenomas

General Information

• These tumors typically cause excessive thyroid function (hyperthyroidism) but occasionally may be associated with reduced thyroid activity (hypothyroidism).
• Because many patients first have thyroid treatment of some sort, these pituitary tumors are often aggressive and invasive.
• They represent just 1 percent to 2 percent of all pituitary adenomas removed via surgery.

Symptoms

• Most patients who have not had prior thyroid therapy will have elevated levels of the hormones thyroxine (T4) and thyrotropin (TSH).

Diagnosis

• Magnetic resonance imaging (MRI) and computed tomography (CT) scans of the pituitary gland typically can identify this type of adenoma.

Treatment

• Transsphenoidal surgery is generally effective. Invasive and very large tumors may require additional therapy, including removal of the thyroid gland or radiation therapy, preferably with stereotactic radiation.

The Neuro-ICU cares for patients with all types of neurosurgical and neurological injuries, including stroke, brain hemorrhage, trauma and tumors. We work in close cooperation with your surgeon or medical doctor with whom you have had initial contact. Together with the surgeon or medical doctor, the Neuro-ICU attending physician and team members direct your family member's care while in the ICU. The Neuro-ICU team consists of the bedside nurses, nurse practitioners, physicians in specialty training (Fellows) and attending physicians. UCLA Neuro ICU Family Guide